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Abstract Modifications on bone surfaces are taphonomic features that allow, among other aspects of environmental reconstruction, the assessment of human presence. The agents that cause such marks are diverse and of both biotic and abiotic origin. Among the former, marks made by human tools are of paramount importance for archaeologists and paleontologists to identify. Although it is possible to erroneously assign trampling marks to cut marks, several criteria have been recently developed so as to avoid such risks. These methods are applied here to the 30,000-year-old site of Arroyo del Vizcaíno (Uruguay), where over one thousand megafaunal remains have been collected. Some of them show marks that have been interpreted to be the result of the action of human tools. Using a database built up from previous studies of experimentally made marks as an actualistic model, it was concluded that the marks in the Arroyo del Vizcaíno site are unlikely to have been made by trampling, hence leaving human agency as the most feasible cause. This has important consequences for the debate on the human peopling of the Americas and on the process of extinction of the Pleistocene megafauna.
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