Background: Aging presents a risk for worsening health and quality of life (QoL). Multisensory stimulation programs (MSP) can promote health and QoL of older adults. Art and Mindfulness are innovative strategies. This study has the following purposes: to present an innovative MSP, with art and strategies based in Mindfulness, of 10 sessions to implement in a group of older adults; to present the verified effects of MSP in cognitive functioning, depressive symptomatology and quality of life of Portuguese older adults. Methods: 33 older adults, aged 65 to 94 years old (M=82.18, SD=7.85), participated in 2 groups, group with intervention (GI, n=16) and a waiting group (GC, n=17). A sociodemographic and clinical questionnaire was used, as well as the following evaluation instruments: Mini Mental State Examination; Patient Health Questionnaire-9; WHOQOL-OLD. We also used the MSP developed, with 10 biweekly sessions. Results: We registered a decrease of depressive symptomatology and an increase of the global and some QoL facets (autonomy; activities, social participation and death), as well as, a decrease of the facet of intimacy from pre to post test of the GI; a decrease of the QoL facet sensory functioning from the pre to post test of the GC. Conclusions: The results obtained allow us to conclude that MSP program, with art and strategies based in Mindfulness, is effective on maintain cognitive function, diminish depressive symptomatology and increase QoL of older adults. Taking into account the importance of the results to “give quality to the years” of older adults, future studies with this and similar programs are encouraged.
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