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In antiquity most of eastern Anatolia was contained within the kingdom of Armenia. As a consequence of the Armenian wars fought in the reign of the emperor Nero, a new dynasty was established on the Armenian throne, that of the Arsacids, a branch of the Parthian royal house. Religion plays a significant role in the struggle over Armenia. The indigenous polytheism had long been mixed with Iranian elements and pagan religion was essentially syncretic. On the eastern borders of Armenia lay the Median march, comprising lands in Atropatene and Adiabene that were wrested from the Persians in 298. To the south were the all-important Syrian and Arabian marches, themselves divided up into a number of autonomous principalities. The Syrian march, formerly the kingdom of Sophene, included the principalities of Ingilene, Anzitene, Lesser and Greater Sophene, each with its own local ruler.
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