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Development of a Cigarette Tobacco Filler Standard Reference Material

Lane C. Sander · Jeanita S. Pritchett · Yasmine C. Daniels · Laura J. Wood · Brian E. Lang · Stephen A. Wise +10 more

6 citations0/0 files storedAnalytical Chemistry

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Scientific Measurement and Uncertainty Evaluation Analytical chemistry methods development Smoking Behavior and Cessation

Abstract

A new tobacco filler Standard Reference Material (SRM) has been issued by the National Institute of Standards and Technology (NIST) in September 2016 with certified and reference mass fraction values for nicotine, N-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, and volatiles. The constituents have been determined by multiple analytical methods with measurements at NIST and at the Centers for Disease Control and Prevention, and with confirmatory measurements by commercial laboratories. This effort highlights the development of the first SRM for reduced nicotine and reduced tobacco-specific nitrosamines with certified values for composition.

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References

2006GUIDE TO THE EXPRESSION OF UNCERTAINTY IN MEASUREMENT 2013Guide to the Expression of Uncertainty in Measurement

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