Death by Gun Violence—A Public Health Crisis

Abstract

subjective awareness of memory function or, as the authors conjecture, more advanced progression leading to reduced awareness of subtle deficits.Although explaining the causes of SCD is important for understanding the mechanisms of AD and its progression, practical implications of this work should be noted.First, many older individuals experience SCD, and physicians need better ways of assessing it to more completely evaluate and counsel their pa-tients.Furthermore, this work and other studies provide mounting evidence that SCD may be an early symptom of the accumulation of AD pathologic change.A better understanding of how each specific molecular pathologic change is expressed in association with SCD at different stages of the development of AD could lead to better methods of diagnosing AD at preclinical stages, selecting individuals for early clinical trials, and ultimately effectively treating AD at its earliest stages.

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