Socioeconomic and Attitudinal Variables Associated with Acceptance and Willingness to Pay Towards Dengue Vaccine: A Systematic Review

Jonny Karunia Fajar · Harapan Harapan

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Vaccine Coverage and Hesitancy Mosquito-borne diseases and control Dengue and Mosquito Control Research

Abstract

Background: Currently, a dengue vaccine has been approved in some countries. The problem with this new vaccine is whether the public could accept and be willing to purchase. Objectives: This study aimed to provide solid data regarding factors associated with acceptance and willingness to pay for dengue vaccine. Methods: A systematic review with a meta-analysis was conducted on September-October 2016 for previous studies. Literatures from PubMed and Embase were searched for eligible publications (cut-off date for updates: September 10, 2016). The combined odds ratios (ORs) and 95% confidence intervals (95% CIs) were assessed using random or fixed effect model. Narrative review was used to analyze the data when they were not qualified for meta-analysis. Results: There were several factors associated with acceptance of dengue vaccine including attitude toward vaccination, preventive measures against dengue, attitude towards dengue, knowledge on dengue, socioeconomic level, and dengue experience. However, our meta-analysis revealed that only attitude towards vaccination (OR95%CI = 0.313 [0.137 - 0.713], P = 0.006) and socioeconomic level (OR95%CI = 0.576 [0.385 - 0.862], P = 0.007) had significant associations with dengue vaccine acceptance. Studies also revealed that preventive measures against dengue, attitude towards dengue, knowledge on dengue fever, knowledge on dengue viruses, socioeconomic levels, dengue experience, and vaccine price were associated with willingness to pay. However, none of those data was qualified for meta-analysis. Conclusions: Meta-analysis reveals that good attitude towards vaccination and higher socioeconomic levels are associated with better acceptance of dengue vaccine.

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References

2014Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature, 2007–2012 2014Attitudes toward vaccination and the H1N1 vaccine: Poor people's unfounded fears or legitimate concerns of the elite?2016Dengue vaccine acceptance and associated factors in Indonesia: A community-based cross-sectional survey in Aceh 2008Childhood vacination in Africa and Asia: the effects of parents' knowledge and attitudes 2012Factors mediating seasonal and influenza A (H1N1) vaccine acceptance among ethnically diverse populations in the urban south 2013If a job is worth doing, it is worth doing twice 2014Attitude toward immunization and risk perception of measles, rubella, mumps, varicella, and pertussis in health care workers working in 6 hospitals of Florence, Italy 2011 2016Dengue vaccine acceptance and willingness to pay

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