Differential Neural Processing of Social Exclusion and Inclusion in Adolescents with Non-Suicidal Self-Injury and Young Adults with Borderline Personality Disorder

Rebecca C. Brown · Paul Lukas Plener · Georg Grön · Dominik Neff · Martina Bonenberger · Birgit Abler

67 citations0/0 files storedFrontiers in Psychiatry

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Death Anxiety and Social Exclusion Suicide and Self-Harm Studies Personality Disorders and Psychopathology

Abstract

Introduction: Non-suicidal self-injury (NSSI) is a symptom of Borderline Personality Disorder (BPD). However, NSSI often occurs independently of BPD. Altered neural processing of social exclusion has been shown in adolescents with NSSI and adults with BPD with additional alterations during social inclusion in BPD patients. Aims of this study were to investigate differences in neural processing of social inclusion and exclusion situations between adolescents with NSSI and young adults with BPD and NSSI. Methods: Using fMRI, neural processing of positive and negative social situations (paradigm: ‘Cyberball’) was explored. Participants were 14 adolescents with NSSI, but without BPD (Mage=15,4; SD=1,9), 15 adults with BPD and NSSI (Mage=23,3; SD=4,1), as well as 15 healthy adolescents (Mage=14,5; SD=1,7) and 16 healthy adults (Mage=23,2; SD=4,4). Results: Behavioral results showed enhanced feelings of social exclusion in both patient groups as compared to healthy controls but only the NSSI group showed enhanced activation during social exclusion vs. inclusion compared to the other groups. While both, NSSI and BPD group showed enhanced activation in the ventral anterior cingulate cortex during social exclusion as compared to their age-matched controls, enhanced activation during social inclusion as compared to a passive watching condition was mainly observed in the BPD group in the dorsolateral and dorsomedial prefrontal cortex, and the anterior insula. Discussion: While neural processing of social exclusion was pronounced in adolescents with NSSI, BPD patients also showed increased activity in a per se positive social situation. These results might point towards a higher responsiveness to social exclusion in adolescents with NSSI, which might then develop into a generalized increased sensitivity to all kind of social situations in adults with BPD.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 67 citations exist upstream.

References

1957A Theory of Cognitive Dissonance 2003Does Rejection Hurt? An fMRI Study of Social Exclusion 2000Cyberostracism: Effects of being ignored over the Internet.2007Self-Injurious Thoughts and Behaviors Interview: Development, reliability, and validity in an adolescent sample.2009A biosocial developmental model of borderline personality: Elaborating and extending linehan’s theory.2012International prevalence of adolescent non-suicidal self-injury and deliberate self-harm 2010Revised NESARC Personality Disorder Diagnoses: Gender, Prevalence, and Comorbidity with Substance Dependence Disorders 2006When inclusion costs and ostracism pays, ostracism still hurts.

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.