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This article describes how Plato proposed the dualistic solution to the mind-body problem, providing an explanation along the lines of his epistemology. Francis Bacon, in 1600, formulated his vision of the scientific method that will be valid until the 1960's when Karl Popper proposed his version, entering into controversy with the Lord Chancellor. Thanks to recent developments in artificial intelligence and computational neuroscience these problems have new empirical tools to be analyzed. An interesting aspect of this research program, better known as neuroeconomics, is the use it makes of the probability calculation tool for dealing with so-called decisions under uncertainty. The paper is an attempt to tell the birth, development, and some examples of these toolboxes, available to all those who want to apply them to improve knowledge inspired organizations.
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