Effectiveness of group cognitive behavioral therapy with mindfulness in end-stage renal disease hemodialysis patients

Bo Kyung Sohn · Yun Kyu Oh · Jung‐Seok Choi · Jiyoun Song · Jung Pyo Lee · Jung Nam An +5 more

54 citations0/0 files storedKidney Research and Clinical Practice

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Mindfulness and Compassion Interventions Dialysis and Renal Disease Management Cancer survivorship and care

Abstract

BACKGROUND: Many patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) experience depression. Depression influences patient quality of life (QOL), dialysis compliance, and medical comorbidity. We developed and applied a group cognitive behavioral therapy (CBT) program including mindfulness meditation for ESRD patients undergoing HD, and measured changes in QOL, mood, anxiety, perceived stress, and biochemical markers. METHODS: We conducted group CBT over a 12-week period with seven ESRD patients undergoing HD and suffering from depression. QOL, mood, anxiety, and perceived stress were measured at baseline and at weeks 8 and 12 using the World Health Organization Quality of Life scale, abbreviated version (WHOQOL-BREF), the Beck Depression Inventory II (BDI-II), the Hamilton Rating Scale for Depression (HAM-D), the Beck Anxiety Inventory (BAI), and the Perceived Stress Scale (PSS). Biochemical markers were measured at baseline and after 12 weeks. The Temperament and Character Inventory was performed to assess patient characteristics before starting group CBT. RESULTS: The seven patients showed significant improvement in QOL, mood, anxiety, and perceived stress after 12 weeks of group CBT. WHOQOL-BREF and the self-rating scales, BDI-II and BAI, showed continuous improvement across the 12-week period. HAM-D scores showed significant improvement by week 8; PSS showed significant improvement after week 8. Serum creatinine levels also improved significantly following the 12 week period. CONCLUSION: In this pilot study, a CBT program which included mindfulness meditation enhanced overall mental health and biochemical marker levels in ESRD patients undergoing HD.

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2013Diagnostic and Statistical Manual of Mental Disorders 1960A RATING SCALE FOR DEPRESSION 1988An inventory for measuring clinical anxiety: Psychometric properties.2012Cognitive Therapy for Depression 2008Diagnostic and Statistical Manual of Mental Disorders 1998Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment 1996Beck Depression Inventory–II 2008Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain, and Illness

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