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A modelling framework for improved design and decision-making in drug development
7 references·0 citing·23 second hop
A modelling framework for improved design and decision-making in drug development (2019)A modelling framework for improved design…Innovation in the pharmaceutical industry: New estimates of R&D costs (2016)Innovation in the pharmaceuti…Biotech R&D spend jumps by more than 15% (2016)Biotech R&D spend jumps by mo…New drugs cost US$2.6 billion to develop (2014)New drugs cost US$2.6 billion…Clinical development success rates for investigational drugs (2014)Clinical development success …Decision‐making in the pharmaceutical industry: analysis of entrepreneurial risk and attitude using uncertain information (2011)Decision‐making in the pharma…How to improve R&D productivity: the pharmaceutical industry's grand challenge (2010)How to improve R&D productivi…Pharmaceutical R&D: the road to positive returns (2009)Pharmaceutical R&D: the road …Judgement under Uncertainty: Heuristics and Biases (1983)Strategic management of small firms in hostile and benign environments (1989)Models of Bounded Rationality (1997)Using scenario planning in regional development context: the challenges and opportunities (2013)Innovating the innovation process: an organisational experiment in global pharma pursuing radical innovation (2014)OPEN INNOVATION AS A FACILITATOR FOR CORPORATE EXPLORATION (2016)Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery (1996)The price of innovation: new estimates of drug development costs (2003)Can the pharmaceutical industry reduce attrition rates? (2004)A Comprehensive Map of FDA-Approved Pharmaceutical Products (2018)Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018 (2020)A Proof for the Queuing Formula: L = λ W (1961)The Goal: A Process of Ongoing Improvement (1984)Cost-Effectiveness in Health and Medicine (1996)Essential medicines for universal health coverage (2016)The High Cost of Prescription Drugs in the United States (2016)Antibody-drug conjugates: Intellectual property considerations (2015)Bridging the translational gap: collaborative drug development and dispelling the stigma of commercialization (2015)The pharmaceutical productivity gap – Incremental decline in R&D efficiency despite transient improvements (2024)Diagnosing the decline in pharmaceutical R&D efficiency (2012)Outlook for the next 5 years in drug innovation (2012)Orphan Drugs and Their Impact on Pharmaceutical Development (2018)Towards reproducible computational drug discovery (2020)
this work references cited by second hop

References

  • 2010How to improve R&D productivity: the pharmaceutical industry's grand challenge3,686 cited
  • 2016Innovation in the pharmaceutical industry: New estimates of R&D costs3,621 cited
  • 2014Clinical development success rates for investigational drugs2,616 cited
  • 2014New drugs cost US$2.6 billion to develop217 cited
  • 2009Pharmaceutical R&D: the road to positive returns95 cited
  • 2016Biotech R&D spend jumps by more than 15%56 cited
  • 2011Decision‐making in the pharmaceutical industry: analysis of entrepreneurial risk and attitude using uncertain information34 cited

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