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The purpose of the article The purpose of the study is to determine the features of factors’ development and systematization affecting the degree of innovation activity and efficiency of projects in the Russian regions. Materials and methods: The main research methods used in the article are the method of description, which allowed determining of the level and trends of Russian regions’ innovative development; the method of cluster analysis for regions’ classification by innovative activity’s parameters in order to identify the characteristics and determine the directions of the target differentiated approach to the development of innovation. Results of the research: The article presents the analysis of innovative development dynamics of the Russian regions’ industrial sector; the tendencies of scientific and innovative activity’s financing in the Federal districts; the regions’ classification by the parameters of innovative activity in order to identify the characteristics of innovations’ development and commercialization. Applications: This research can be used for universities, teachers, and students. Novelty/Originality: In this research, the model of differentiated approach problems to innovative development management in Russian regions is presented in a comprehensive and complete manner.
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