Affect Dynamics as Predictors of Symptom Severity and Treatment Response in Mood and Anxiety Disorders: Evidence for Specificity

Abstract

(the extent to which emotions self-perpetuate over time, the lag-1 autocorrelation of the vector). Multiple regression models were run to test dynamics of positive and negative affect as between-subjects predictors of symptom severity and pre-to-posttreatment change in symptoms. Findings suggest NA dynamics are unrelated to depression symptom severity or treatment response, but we observed a specific effect of NA instability (MSSD) on both severity and response of anxiety symptoms. All PA dynamics were unrelated to anxiety or depression symptom severity. However, variability, instability, and inertia of PA were all found to relate to treatment response for both anxiety and depression symptoms. Taken together, our results suggest that affect dynamics have some specificity in their relationship to clinically relevant phenomena such as symptom severity and treatment outcomes at the between-subjects level of analysis.

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