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Loneliness, social isolation, cardiovascular disease and mortality: a synthesis of the literature and conceptual framework

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References

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2013Social isolation, loneliness, and all-cause mortality in older men and women2,504 cited
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2016Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies1,968 cited
2006Social Isolation in America: Changes in Core Discussion Networks over Two Decades1,887 cited
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2008Conducting a meta-ethnography of qualitative literature: Lessons learnt980 cited
2015Loneliness as a Public Health Issue: The Impact of Loneliness on Health Care Utilization Among Older Adults781 cited
2017Social prescribing: less rhetoric and more reality. A systematic review of the evidence

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780 cited

2010Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults.726 cited

2018Association of loneliness with all-cause mortality: A meta-analysis651 cited

2003The Anatomy of Loneliness396 cited

Cited by

2024The associations of socioeconomic status, social activities, and loneliness with depressive symptoms in adults aged 50 years and older across 24 countries: findings from five prospective cohort studies172 cited
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2021Social isolation, social support and loneliness as independent concepts, and their relationship with health-related quality of life among older women109 cited
2024The impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation79 cited
2025Plasma proteomic signatures of social isolation and loneliness associated with morbidity and mortality75 cited
2021Social isolation, social support, loneliness and cardiovascular disease risk factors: A cross‐sectional study among older adults71 cited
2023Social connection and mortality in UK Biobank: a prospective cohort analysis64 cited
2022Affective Neuroscience of Loneliness: Potential Mechanisms underlying the Association between Perceived Social Isolation, Health, and Well-Being63 cited
2023Association of Social Isolation With Hospitalization and Nursing Home Entry Among Community-Dwelling Older Adults47 cited
2023The relationship between social isolation, social support, and loneliness with cardiovascular disease and shared risk factors: A narrative review45 cited
2022Loneliness, Social Isolation, and Living Alone Associations With Mortality Risk in Individuals Living With Cardiovascular Disease: A Systematic Review, Meta-Analysis, and Meta-Regression43 cited
20242024 ACC/AHA Key Data Elements and Definitions for Social Determinants of Health in Cardiology: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Data Standards43 cited
2023Social isolation and loneliness: Undervalued risk factors for disease states and mortality39 cited
2022Are social isolation, lack of social support or loneliness risk factors for cardiovascular disease in Australia and New Zealand? A systematic review and meta‐analysis37 cited
2023National Health Guidelines for Social Connection: What Is the Evidence in Support and What Might the Guidelines Say?34 cited