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Background: The outbreak and spread of a novel coronavirus disease (COVID-19) led to a confinement situation in many countries worldwide. Our objective was to analyze the short-term psychological effects of the COVID-19 crisis and the quarantine on the population. Methods: A cross-sectional study was conducted. A survey was completed by 3550 adults from Spain. Symptoms of anxiety, depression and stress were analyzed using the 21-item version of the Depression Anxiety Stress Scale. Symptoms of posttraumatic stress disorder were analyzed using the Impact of Event Scale. Results: Symptomatic scores of anxiety, depression, stress were observed in 32.4%, 44.1% and 37.0% of respondents, respectively. Also, symptomatic scores indicating psychological stress were found in 88.6% of respondents. Increased prevalence of anxiety, depression and stress symptoms was associated with female sex, younger age, self-reported COVID-19 symptoms, previous psychological or psychiatric treatment, intake of psychoactive medication and negative effect on social relationships and relationships with people living in the same place. Higher scores related to symptoms of posttraumatic stress disorder was associated with most of those factors, and also with the acquaintance with a COVID-19 patient.Conclusion: An important emotional impact of confinement related to COVID-19 has been found in Spanish population. Considering a possible long period of confinement, the evolution of the psychological effects should be controlled to prevent severe mental health disorders.
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