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Factors Influencing SARS-CoV-2 Vaccine Acceptance and Hesitancy in a Population-Based Sample in Italy

Marco Del Riccio · Sara Boccalini · Lisa Rigon · Massimiliano Alberto Biamonte · Giuseppe Albora · Duccio Giorgetti +2 more

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Vaccine Coverage and Hesitancy SARS-CoV-2 and COVID-19 Research COVID-19 and Mental Health

Abstract

Vaccination against SARS-CoV-2 represents an effective and safe tool to protect the population against the disease; however, COVID-19 vaccine hesitancy could be a major barrier to achieving herd immunity. Despite the severity of the current pandemic, the population's intention to get vaccinated against COVID-19 is still not clear. The aim of this study was to evaluate the intention to get vaccinated against COVID-19 among a convenience sample of the general population resident in Italy and the factors associated with hesitancy and acceptance of the vaccine in the context of the current pandemic before the rolling out of COVID-19 vaccines. An anonymous online survey was diffused among a general adult population living in Italy. Participants aged 18 or older and living in Italy were considered eligible. Incomplete questionnaires were excluded. Overall, 7605 valid questionnaires were collected. Most of the participants (81.9%) were inclined to get vaccinated; male sex (OR 1.38, 95% CI 1.12-1.71), a high level of trust in institutions (OR 3.93, 95% CI 2.04-7.83), and personal beliefs about high safety of COVID-19 vaccines (OR 56.33, 95% CI 31.57-105.87) were found to be among the significant predictors of COVID-19 acceptance. These data could help design larger studies to address the problem of COVID-19 vaccine hesitancy in the current pandemic.

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References

2015Vaccine hesitancy: Definition, scope and determinants 2013Vaccine hesitancy 2020Vaccine hesitancy: the next challenge in the fight against COVID-19 2021Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom 2016The State of Vaccine Confidence 2016: Global Insights Through a 67-Country Survey 2020Attitudes Toward a Potential SARS-CoV-2 Vaccine 2020Once we have it, will we use it? A European survey on willingness to be vaccinated against COVID-19 2020Acceptance of COVID-19 Vaccination during the COVID-19 Pandemic in China

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2022COVID-19 vaccine hesitancy among undocumented migrants during the early phase of the vaccination campaign: a multicentric cross-sectional study 2023COVID-19 Vaccine Refusal and Delay among Adults in Italy: Evidence from the OBVIOUS Project, a National Survey in Italy 2022Reasons for COVID-19 Vaccine Hesitancy Among Chinese People Living With HIV/AIDS: Structural Equation Modeling Analysis 2021Anti-COVID Vaccination for Adolescents: A Survey on Determinants of Vaccine Parental Hesitancy

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