Review2021

Intention to Receive COVID-19 Vaccine during Pregnancy: A Systematic Review and Meta-analysis

Alireza Abdollah Shamshirsaz · Kamran Hessami · Stephanie R. Morain · Yalda Afshar · Ahmed Abobakr Nassr · Sara Elizabeth Arian +2 more

42 citations0/0 files storedAmerican Journal of Perinatology

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Vaccine Coverage and Hesitancy SARS-CoV-2 and COVID-19 Research COVID-19 Impact on Reproduction

Abstract

OBJECTIVE: This meta-analysis aimed to assess the level of intent to receive coronavirus disease 2019 (COVID-19) vaccination and demographical factors influencing vaccine uptake among pregnant individuals. STUDY DESIGN: PubMed, Scopus, and archive/pre-print servers were searched up to May 22nd, 2021. Cross sectional surveys reporting the percentage of the pregnant individuals intending to get a COVID-19 vaccine were considered eligible for meta-analysis. This review was registered with PROSPERO (CRD42021254484). The primary outcome was to estimate the prevalence of COVID-19 vaccination intent among pregnant population. The secondary outcome was to evaluate the factors influencing the intention for vaccination. RESULTS: = 0.006). CONCLUSION: The intent to receive COVID-19 vaccine is relatively low among women who are pregnant and substantially varies based on the country of residence. In our meta-analysis, intent of women who were pregnant to receive the COVID-19 vaccine was significantly associated with the history of receiving influenza or TdaP vaccine during pregnancy. Given that in every country only a minority of gravidae have received the COVID-19 vaccine, despite known risks of maternal morbidity and mortality with no evidence of risks of vaccination, it highlights the importance of revised approaches at shared decision making and focused public health messaging by national and international advisories. KEY POINTS: · The estimated global intention for COVID-19 vaccination among pregnant women was 47%.. · The lowest intention was in Africa and the highest in Oceania.. · These findings highlight the importance of public health messaging by by different agencies..

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References

2020Attitudes Toward a Potential SARS-CoV-2 Vaccine 2021COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries 2021International estimates of intended uptake and refusal of COVID-19 vaccines: A rapid systematic review and meta-analysis of large nationally representative samples 2021COVID‐19 vaccine acceptance in pregnant women 2021Willingness to Vaccinate Against COVID-19 in the U.S.: Representative Longitudinal Evidence From April to October 2020 2022Women’s views on accepting COVID-19 vaccination during and after pregnancy, and for their babies: a multi-methods study in the UK 2021Acceptance of a COVID-19 vaccine and associated factors among pregnant women in China: a multi-center cross-sectional study based on health belief model 2021COVID-19 vaccine acceptance among pregnant, breastfeeding, and nonpregnant reproductive-aged women

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2023Barriers and facilitators of vaccine hesitancy for COVID-19, influenza, and pertussis during pregnancy and in mothers of infants under two years: An umbrella review 2022COVID-19 vaccine acceptance and coverage among pregnant persons in the United States 2023The determinants of COVID-19 vaccination intention: a meta-review

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