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No alternative to human blood has been found so far, and the only source is blood donation by donors. This study presents a blood supply chain optimization model focusing on the location and inventory management of different centers. The main purpose of this model is to reduce total costs, including hospital construction costs, patient allocation costs, patient service costs, expected time-out fines, non-absorbed blood fines, and outsourcing process costs. We then calculate the cost savings of collaborating in each hospital coalition to calculate the fair allocation of cost savings across hospitals. The proposed model is developed based on the data for the city of Tehran and previous studies in the field of the blood supply chain as well as using four Cooperative Game Theory (CGT) methods such as Shapley value, τ- Value, core-center and least core, to reduce the total cost and the fair profit sharing between hospitals have been evaluated.
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