A Battle against COVID-19: Vaccine Hesitancy and Awareness with a Comparative Study between Sinopharm and AstraZeneca

Marian S. Boshra · Raghda R. S. Hussein · Marwa Mohsen · Ahmed Abdullah Elberry · Ahmed Essam Altyar · Rania M. Sarhan

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Vaccine Coverage and Hesitancy Pharmacovigilance and Adverse Drug Reactions SARS-CoV-2 and COVID-19 Research

Abstract

BACKGROUND: Awareness about the COVID-19 vaccine's adverse effects is crucial for gaining public trust. As we still lack proof of vaccines' safety, this survey aimed to investigate Egyptians' general awareness of the Sinopharm and AstraZeneca vaccines against COVID-19 and provide considerable evidence on their side effects and complications. METHODS: A cross-sectional questionnaire-based study was conducted in Egypt between 20 September and 10 October in 2021, with multiple-choice questions (MCQs) covering all data on vaccine administration confusion, adverse effects or intensity, and complications. RESULTS: Among the 390 participants, 42.3% reported being hesitant before receiving one of the vaccines. About 40.3% of participants were previously infected before getting vaccinated while only 4.6% reported being infected after vaccination. The AstraZeneca vaccine demonstrated higher side effects and symptoms than the Sinopharm vaccine while the Sinopharm vaccine showed a significantly higher rate of COVID-19 infection after vaccination. CONCLUSIONS: People with higher educational levels and chronic respiratory diseases represent an excellent model for accepting COVID-19 vaccination. A booster shot is recommended for people vaccinated with the Sinopharm vaccine due to a significantly higher rate of COVID-19 infection after vaccination; however, the Sinopharm vaccine shows a more acceptable safety profile.

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2020A global survey of potential acceptance of a COVID-19 vaccine 2020Vaccine hesitancy: the next challenge in the fight against COVID-19 2020Susceptibility to misinformation about COVID-19 around the world 2020Confidence and Receptivity for COVID-19 Vaccines: A Rapid Systematic Review 2021COVID-19 vaccine hesitancy in a representative working-age population in France: a survey experiment based on vaccine characteristics 2020COVID-19 vaccination intention in the UK: results from the COVID-19 vaccination acceptability study (CoVAccS), a nationally representative cross-sectional survey 2021COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries 2021Vaccine hesitancy: Beliefs and barriers associated with COVID‐19 vaccination among Egyptian medical students

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2022Acceptance, Hesitancy, and Refusal in Anti-COVID-19 Vaccination: A Cluster Analysis Aiming at the Typology behind These Three Concepts 2023Hesitancy toward vaccination against COVID-19: A scoping review of prevalence and associated factors in the Arab world

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