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Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis
14 references·8 citing·49 second hopsampled
Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis (2022)Nonregistration, discontinuation, and non…Reporting guideline checklists are not quality evaluation forms: they are guidance for writing (2020)Reporting guideline checklist…Prospective registration and reporting of trial number in randomised clinical trials: global cross sectional study of the adoption of ICMJE and Declaration of Helsinki recommendations (2020)Prospective registration and …COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time (2019)COMPare: a prospective cohort…Registration of published randomized trials: a systematic review and meta-analysis (2018)Registration of published ran…Does the medical literature remain inadequately described despite having reporting guidelines for 21 years? – A systematic review of reviews: an update (2018)Does the medical literature r…Adherence to the International Committee of Medical Journal Editors’ (ICMJE) prospective registration policy and implications for outcome integrity: a cross-sectional analysis of trials published in high-impact specialty society journals (2018)Adherence to the Internationa…When are clinical trials registered? An analysis of prospective versus retrospective registration (2016)When are clinical trials regi…Extent of Non-Publication in Cohorts of Studies Approved by Research Ethics Committees or Included in Trial Registries (2014)Extent of Non-Publication in …SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials (2013)SPIRIT 2013 Statement: Defini…SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials (2013)SPIRIT 2013 explanation and e…Reporting and Interpretation of Randomized Controlled Trials With Statistically Nonsignificant Results for Primary Outcomes (2010)Reporting and Interpretation …Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors (2005)Is this clinical trial fully …Empirical Evidence for Selective Reporting of Outcomes in Randomized Trials (2004)Empirical Evidence for Select…Registering Clinical Trials (2003)Registering Clinical TrialsReporting summary results in clinical trial registries: updated guidance from WHO (2025)Reporting summary results in …Nonregistration, Discontinuation, and Nonpublication of Randomized Trials (2025)Nonregistration, Discontinuat…Time to publication for results of clinical trials (2024)Time to publication for resul…Nudging in clinical trial registration (2023)Nudging in clinical trial reg…Institutional dashboards on clinical trial transparency for University Medical Centers: A case study (2023)Institutional dashboards on c…Dissemination of the Results of Pediatric Clinical Trials Funded by the US National Institutes of Health (2023)Dissemination of the Results …A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols (2022)A meta-research study of rand…A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study (2022)A longitudinal assessment of …Measuring inconsistency in meta-analyses (2003)Why Most Published Research Findings Are False (2005)Why Most Published Research Findings Are False (2005)Catalogue of bias: publication bias (2018)Tools for assessing risk of reporting biases in studies and syntheses of studies: a systematic review (2018)Considering bias and conflicts of interest among the included studies (2019)Publication Decisions and their Possible Effects on Inferences Drawn from Tests of Significance—or Vice Versa (1959)Publication bias: the case for an international registry of clinical trials. (1986)Publication bias and clinical trials (1987)Reporting bias in medical research - a narrative review (2010)Pre-registration in social psychology—A discussion and suggested template (2016)Full publication of results initially presented in abstracts (2018)The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration (2001)Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias (2008)Does Cultural Competency Training of Health Professionals Improve Patient Outcomes? A Systematic Review and Proposed Algorithm for Future Research (2010)Retractions in the scientific literature: is the incidence of research fraud increasing? (2010)Evolution of Reporting P Values in the Biomedical Literature, 1990-2015 (2016)The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials (2001)The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials (2001)Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis (2007)Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry (2008)CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials (2010)CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials (2010)CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomized Trials (2010)Reporting of Patient-Reported Outcomes in Randomized Trials (2013)Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement (2015)The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration (2009)The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration (2009)Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide (2014)Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation (2015)Full publication of results initially presented in abstracts (2007)The cumulative effect of reporting and citation biases on the apparent efficacy of treatments: the case of depression (2018)Big little lies: a compendium and simulation of p -hacking strategies (2023)Effect of the Statistical Significance of Results on the Time to Completion and Publication of Randomized Efficacy Trials (1998)Comparison of Registered and Published Primary Outcomes in Randomized Controlled Trials (2009)Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias — An Updated Review (2013)More systematic reviews were registered in PROSPERO each year, but few records' status was up-to-date (2019)The Effect of Mindfulness-based Programs on Cognitive Function in Adults: A Systematic Review and Meta-analysis (2021)Clinical trial registration was associated with lower risk of bias compared with non-registered trials among trials included in systematic reviews (2022)The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies (2007)The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies (2007)Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement (2009)Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024 (2024)Guideline for reporting systematic reviews of outcome measurement instruments (OMIs): PRISMA-COSMIN for OMIs 2024 (2024)CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials (2010)The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews (2010)Comparing dream to reality: an assessment of adherence of the first generation of preregistered studies (2021)Reducing bias, increasing transparency and calibrating confidence with preregistration (2023)CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials (2025)
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References

  • 2013SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials7,356 cited
  • 2013SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials6,239 cited
  • 2004Empirical Evidence for Selective Reporting of Outcomes in Randomized Trials1,845 cited
  • 2010Reporting and Interpretation of Randomized Controlled Trials With Statistically Nonsignificant Results for Primary Outcomes828 cited
  • 2003Registering Clinical Trials511 cited
  • 2014Extent of Non-Publication in Cohorts of Studies Approved by Research Ethics Committees or Included in Trial Registries269 cited
  • 2019COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time232 cited
  • 2018Does the medical literature remain inadequately described despite having reporting guidelines for 21 years? – A systematic review of reviews: an update134 cited
  • 2018Registration of published randomized trials: a systematic review and meta-analysis107 cited
  • 2016When are clinical trials registered? An analysis of prospective versus retrospective registration104 cited
  • 2020Reporting guideline checklists are not quality evaluation forms: they are guidance for writing93 cited
  • 2005Is this clinical trial fully registered? A statement from the International Committee of Medical Journal Editors91 cited
  • 2020Prospective registration and reporting of trial number in randomised clinical trials: global cross sectional study of the adoption of ICMJE and Declaration of Helsinki recommendations

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89 cited
  • 2018Adherence to the International Committee of Medical Journal Editors’ (ICMJE) prospective registration policy and implications for outcome integrity: a cross-sectional analysis of trials published in high-impact specialty society journals79 cited
  • Cited by

    • 2024Time to publication for results of clinical trials31 cited
    • 2025Reporting summary results in clinical trial registries: updated guidance from WHO24 cited
    • 2022A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study21 cited
    • 2023Dissemination of the Results of Pediatric Clinical Trials Funded by the US National Institutes of Health19 cited
    • 2022A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols17 cited
    • 2025Nonregistration, Discontinuation, and Nonpublication of Randomized Trials13 cited
    • 2023Institutional dashboards on clinical trial transparency for University Medical Centers: A case study12 cited
    • 2023Nudging in clinical trial registration1 cited