Assessment of biological maturation

Abstract

Abstract The processes of growth and maturation occur concurrently and are related. Chapter 1 discusses indicators of growth status and rate followed by a description of methods for assessment of maturity status and timing. Status refers to the state of maturation at the time of observation. Skeletal age and stages of puberty indicate status. Timing refers to the chronological age at which specific maturational events occur. Ages at peak height velocity (PHV) and at menarche are used most often. Skeletal age is applicable from childhood through adolescence; other indicators of status and timing are limited to the interval of puberty and the growth spurt. Increasingly used non-invasive indicators of maturation include percentage of predicted adult height attained at the time of observation (status) and predicted maturity offset or time before age at PHV (timing). Both have limitations and require further validation.

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