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Behavioral activation (BA) treatment has evolved from a component of cognitive behavioral therapy (CBT) and has become standalone psychotherapy for depression. The rapid increasing application of tele-mental health approaches such as telephone-, internet-, and smartphone-based interventions with BA were emphasized. With its efficacy comparable to traditional CBT, and its evidenced-based cost-effectiveness, BA is promising to be developed into a guided self-help intervention. The efficacy across diagnoses and effective components of BA treatment were reviewed. With the rise of the third wave of psychotherapy, therapeutic components across diagnoses will be incorporated into behavioral activation therapy. However, extensive studies are required to examine the neural and modulatory mechanism of BA for depression, and to explore the feasibility and necessity of tele-mental health BA application into the healthcare system.
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