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This is the text of the Fifteenth Fisher Memorial Lecture, presented at the Senate House, Cambridge on 23 March 1990, on the centenary of R. A. Fisher’s birth. R. A. Fisher. (Photograph by Antony Barrington-Brown, A. R. P. S.) R. A. Fisher was undoubtedly one of the greatest scientists of this century, a man of extraordinary ability and originality whose achievements included establishing statistics on a modern footing and providing the key contribution to establishing the quantitative theory of evolution based on Mendelian genetics. R. A. Fisher will always be one of my greatest heroes, but no doubt I am influenced in my view because I was amongst the last of his disciples and because he established the initial sequence of my career, which became essentially a sequence of different activities in genetics.
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