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The Russian economy is currently experiencing major transformations. Under these conditions, the issues of research advancement, technological development, and import substitutions are relevant both at the federal and regional levels. The present research featured some theoretical aspects of developing a new strategy for the scientific and technological advancement of the Tatarstan Republic, as well as the main tools and directions of its implementation. The article introduces the main trends that must be taken into account and the opportunities, threats and risks that take place in the real economy of the Republic of Tatarstan. The obtained results can be of practical use for specialists involved in strategy development.
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