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Subject. The innovation activity of entrepreneurial structures within certain regional economic systems and its significant impact on the gross regional product. Objectives. The purpose of this study was to identify the relationship between the innovative activity of entrepreneurial structures and the effectiveness of the regional economy. Methods. Statistical methods and linear predictive models were used. Results. It was proved that the growth in the volume of innovative goods, works, services, as well as the costs of innovative activities of organizations is accompanied by an increase in GRP. The revealed relationship between these factors is of the same type, unidirectional and linear, characterized by a high degree of significance and reliability. However, there is no statistically significant relationship between the specific weight of enterprises engaged in innovative activities and the value of GRP. Conclusions. Dependence of gross regional product on innovation costs requires increased investment in technological modernization of production.
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