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Identifying and managing problematic trials: A research integrity assessment tool for randomized controlled trials in evidence synthesis
7 references·11 citing·37 second hop
Identifying and managing problematic trials: A research integrity assessment tool for randomized controlled trials in evidence synthesis (2022)Identifying and managing problematic tria…False individual patient data and zombie randomised controlled trials submitted to Anaesthesia (2020)False individual patient data…Cochrane Handbook for Systematic Reviews of Interventions (2020)Cochrane Handbook for Systema…Check for publication integrity before misconduct (2020)Check for publication integri…CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials (2010)CONSORT 2010 Statement: updat…CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials (2010)CONSORT 2010 Statement: updat…Cochrane Handbook for Systematic Reviews of Interventions (2008)Cochrane Handbook for Systema…[The International Clinical Trials Registry Platform - ICTRP]. (2007)[The International Clinical T…INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials (2025)INSPECT-SR: a tool for assess…Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project (2025)Assessing the feasibility and…Tools, techniques, methods, and processes for the detection and mitigation of fraudulent or erroneous data in evidence synthesis: a scoping review protocol (2024)Tools, techniques, methods, a…The Individual Participant Data Integrity Tool for assessing the integrity of randomised trials (2024)The Individual Participant Da…Research Integrity in Guidelines and evIDence synthesis (RIGID): a framework for assessing research integrity in guideline development and evidence synthesis (2024)Research Integrity in Guideli…Publication integrity: what is it, why does it matter, how it is safeguarded and how could we do better? (2024)Publication integrity: what i…Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions (2024)Protocol for the development …Enhancing the trustworthiness of pain research: A call to action. (2024)Enhancing the trustworthiness…Trials We Cannot Trust: Investigating Their Impact on Systematic Reviews and Clinical Guidelines in Spinal Pain (2023)Trials We Cannot Trust: Inves…Predatory journals and their practices present a conundrum for systematic reviewers and evidence synthesisers of health research: A qualitative descriptive study (2023)Predatory journals and their …Improving trustworthiness in research in women's health: A collective effort by OBGYN editors (2023)Improving trustworthiness in …Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials (1995)Assessing the quality of reports of randomized clinical trials: Is blinding necessary? (1996)The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials (2001)Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement (2009)The PRISMA 2020 statement: an updated guideline for reporting systematic reviews (2021)The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies (2007)Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement (2009)Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement. (2009)Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide (2014)Standards for Reporting Qualitative Research (2014)Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation (2015)Why Has the Number of Scientific Retractions Increased? (2013)A review of the current concerns about misconduct in medical sciences publications and the consequences (2020)Data integrity of 35 randomised controlled trials in women’ health (2020)Methods to assess research misconduct in health-related research: A scoping review (2021)Why Most Published Research Findings Are False (2005)Why Most Published Research Findings Are False (2005)The analysis of 168 randomised controlled trials to test data integrity (2012)Hundreds of thousands of zombie randomised trials circulate among us (2020)Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed? (2023)The Cochrane Collaboration's tool for assessing risk of bias in randomised trials (2011)RoB 2: a revised tool for assessing risk of bias in randomised trials (2019)Checklist to assess Trustworthiness in RAndomised Controlled Trials (TRACT checklist): concept proposal and pilot (2023)Investigating the impact of trial retractions on the healthcare evidence ecosystem (VITALITY Study I): retrospective cohort study (2025)But is it rigorous? Trustworthiness and authenticity in naturalistic evaluation (1986)Avoidable waste in the production and reporting of research evidence (2009)A manifesto for reproducible science (2017)Evidence-Based Medicine, Systematic Reviews, and Guidelines in Interventional Pain Management: Part 2: Randomized Controlled Trials (2008)Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment (2013)10 Steps to Conduct a Systematic Review (2023)CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials (2010)SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials (2013)Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration (2015)Positive psychology interventions: a meta-analysis of randomized controlled studies (2013)AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both (2017)Declaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas (2021)Assessing the coverage of PubMed, Embase, OpenAlex, and Semantic Scholar for automated single-database searches in living guideline evidence surveillance: a case study of the international polycystic ovary syndrome guidelines 2023 (2025)
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References

  • 2008Cochrane Handbook for Systematic Reviews of Interventions25,045 cited
  • 2010CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials13,365 cited
  • 2010CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials9,314 cited
  • 2020Cochrane Handbook for Systematic Reviews of Interventions5,670 cited
  • 2020False individual patient data and zombie randomised controlled trials submitted to Anaesthesia172 cited
  • 2007[The International Clinical Trials Registry Platform - ICTRP].158 cited
  • 2020Check for publication integrity before misconduct113 cited

Cited by

  • 2024Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions45 cited
  • 2024Research Integrity in Guidelines and evIDence synthesis (RIGID): a framework for assessing research integrity in guideline development and evidence synthesis35 cited
  • 2024Enhancing the trustworthiness of pain research: A call to action.29 cited
  • 2025Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project28 cited
  • 2024The Individual Participant Data Integrity Tool for assessing the integrity of randomised trials27 cited
  • 2023Trials We Cannot Trust: Investigating Their Impact on Systematic Reviews and Clinical Guidelines in Spinal Pain

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26 cited
  • 2024Publication integrity: what is it, why does it matter, how it is safeguarded and how could we do better?25 cited
  • 2025INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials15 cited
  • 2023Predatory journals and their practices present a conundrum for systematic reviewers and evidence synthesisers of health research: A qualitative descriptive study12 cited
  • 2024Tools, techniques, methods, and processes for the detection and mitigation of fraudulent or erroneous data in evidence synthesis: a scoping review protocol9 cited
  • 2023Improving trustworthiness in research in women's health: A collective effort by OBGYN editors7 cited