Core outcome sets in medical research

Jamie J Kirkham · Paula Ruth Williamson

111 citations0/0 files storedBMJ Medicine

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Delphi Technique in Research Health Systems, Economic Evaluations, Quality of Life Meta-analysis and systematic reviews

Abstract

### Key messages > Jamie Kirkham and Paula Williamson outline the importance of core outcome sets in medical research, and make suggestions on how to identify, select, and develop them as well as highlight some of the barriers to their use A core outcome set helps researchers to measure a

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2009Avoidable waste in the production and reporting of research evidence 2017The COMET Handbook: version 1.0 2012Developing core outcome sets for clinical trials: issues to consider 2016How to select outcome measurement instruments for outcomes included in a “Core Outcome Set” – a practical guideline 2017Core Outcome Set-STAndards for Development: The COS-STAD recommendations 2017A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis 2019Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research 2020A systematic review finds Core Outcome Set uptake varies widely across different areas of health

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