Delayed adverse reactions in whole blood donors

Abhaykumar Malind Gupta · Meenu Bajpai

4 citations0/0 files storedThe Indian Journal of Medical Research

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Blood donation and transfusion practices Pharmacovigilance and Adverse Drug Reactions Blood transfusion and management

Abstract

Background & objectives: The information available regarding delayed adverse donor reactions (D-ADRs) is limited. Proactive follow up of donors for delayed reactions is not done routinely. This study was undertaken to analyze frequency and type of D-ADRs in whole blood donors as also the contributory factors. Methods: In this prospective observational study, all eligible whole blood donors were contacted telephonically twice (24 h and 2 wks after donation) and asked about general health and ADR specific questions. The International Society of Blood Transfusion standard guidelines were used to categorize ADRs. Results: The ADR data of 3514 donors were analyzed in the study. D-ADRs were more common as compared to immediate delayed adverse donor reactions (I-ADRs) (13.7 vs. 2.9%, P<0.001). The most common D-ADRs were bruises (4.98%), fatigue or generalized weakness (4.24%) and sore arms (2.25%). D-ADRs were more common in first time donors as compared to the repeat blood donors (16.1 vs. 12.5%, P=0.002). Females were more prone to D-ADRs (17 vs. 13.6%). Localized D-ADRs were more frequent as compared to systemic D-ADRs (P<0.001). Repeat donors had a lower incidence of systemic D-ADRs (4.11% vs. 7.37%, P<0.001). Interpretation & conclusions: D-ADRs were more common than I-ADRs with a different profile. First time, female and young donors were more prone to D-ADRs. These categories need special care at the time of blood donation. Active follow up of blood donors should be done from time to time to strengthen donor safety.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 4 citations exist upstream.

References

2003Adverse effects in blood donors after whole‐blood donation: a study of 1000 blood donors interviewed 3 weeks after whole‐blood donation 2009BLOOD DONORS AND BLOOD COLLECTION: Delayed adverse reactions to blood donation 2011Adverse reactions and other factors that impact subsequent blood donation visits 2012Analysis of adverse events and predisposing factors in voluntary and replacement whole blood donors: A study from north India 2012The influence of adverse reactions, subjective distress, and anxiety on retention of first‐time blood donors 2002[Adverse reactions of blood donation].2016Post-donation telephonic interview of blood donors providing an insight into delayed adverse reactions: First attempt in India 2004Adverse effects in blood donors after whole‐blood donation: you find what you look for!

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.