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Abstract— The article analyzes the innovative-resource directions for the development of industry in the South of the Tyumen oblast (subject of the Russian Federation–the Tyumen oblast without okrugs—STO) based on the concepts of evolutionary economic geography and the theory of innovation. It is shown that the development of the South of the Tyumen oblast economy is associated with the formation of an oil industry cluster, deep processing of hydrocarbon raw materials, and the development of oil and gas resources. The development of the noted areas is largely determined by the already created innovative and industrial potential, long-term cooperation with the oil and gas regions of Western Siberia, and the prospects for the development of the oil and gas sector. The effective development of these areas requires the formation and implementation of a targeted policy of the region, focused, among other things, on the development of its own innovative companies, attracting new knowledge and competencies from other regions.
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