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Subject. This article examines the system of relations between the State, business and society regarding the development of industry in the regions of Russia in the context of sanctions. Objectives. The article aims to identify tactical measures that neutralize the impact of large-scale anti-Russian sanctions, and substantiate the strategic directions of development of the regional industry in the face of increasing geopolitical uncertainty. Methods. For the study, we used structural, comparative, and statistical analyses. Results. The article proposes and systematizes measures to support industry in the regions of the Ural Federal District. It also identifies strategic priorities for the development of industry and proposes the concept of industrial policy of the Ural Federal District. Conclusions. The strategic vector of industrial development of the Ural Federal District is determined by the significant production, scientific, technological and educational potential of the region, the implementation of which will improve the standard of living of the population and ensure the contribution of the Ural industry to the achievement of Russia's technological sovereignty.
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