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The specifics of Russian economic cycles, in particular, is that their course differs markedly in different regions, resulting in increased asymmetry in regional development. The paper studied of the influence of historical and sectoral factors, which determine the economic specialisation of the region, and the features of the sectoral structure of the regional economic in growth of the old industrial regions of Russia. Thus, the author concluded the nature of their dynamics mainly determines the sectoral factor and revealed a significant number of promising economic specialisations is a characteristic of the old industrial territories in virtue of the historical features of the industry growth in the Soviet period and the external position of economic activity. The outcome is that it is necessary to conduct a selective regional policy aimed at overcoming the limitations of the resource, organizational, and institutional nature of the development of old industrial regions.
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