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Abstract Purpose To explore the mediating effect of hope in the relationships between social support and self-esteem with psychological resilience among patients with stroke survivors in early rehabilitation. Methods A cross-sectional study design was adopted. Data from a cross-sectional survey of 210 patients undergoing early stroke rehabilitation were analysed using structural equation modelling. The variables of interest were measured using the Connor Davidson Resilience Scale, the Social Support Rating Scale, the Herth Hope Index, and the Self-Esteem Scale. This article reports according to the STROBE checklist. Results A positive relationship was found between social support and psychological resilience (β1 = .548), which was mediated by hope (β2 = .114), and social support had significant direct effect on resilience (β3 = .434). A positive relationship was also found between self-esteem and psychological resilience (β4 = .380), which was mediated by hope (β5 = .200), and self-esteem had significant direct effect on resilience (β6 = .179). Conclusion According to the results of this study, some strategies can be incorporated into the rehabilitation process to enhance psychological resilience, such as cultivating individual personality characteristics and improving patients’ social relationships. In the future, we need to explore methods for improving psychological resilience among patients with stroke in combination with their risk factors to improve their quality of life and reduce the incidence of post-stroke depression.
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