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Introduction: transfusion safety is critical to prevent potentially severe adverse effects. A possible relationship between knowledge of health laws and management control in the Hemotherapy and Blood Bank Program of an EsSalud hospital in Peru was analyzed.Objective: to determine whether greater knowledge of current regulations is associated with better management control practices and decreased transfusion risks.Methods: observational, cross-sectional study in 319 participants through validated surveys to measure variables of interest. Analysis with descriptive statistics, chi square and Spearman correlation.Results: a significant association was found between greater knowledge of health laws with better management control, decreased potential risks and greater user satisfaction (p<0,05).Conclusions: it is essential to train health personnel in current legislation and regulations to optimize transfusion safety and quality
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