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A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Effect of Eszopiclone 2 mg on Sleep/Wake Function in Older Adults with Primary and Comorbid Insomnia
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A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Effect of Eszopiclone 2 mg on Sleep/Wake Function in Older Adults with Primary and Comorbid Insomnia (2010)A 12-Week, Randomized, Double-Blind, Plac…Poor Sleep is Associated with Poorer Physical Performance and Greater Functional Limitations in Older Women (2007)Poor Sleep is Associated with…Sleep: A Marker of Physical and Mental Health in the Elderly (2006)Sleep: A Marker of Physical a…Poor Sleep Is Associated With Impaired Cognitive Function in Older Women: The Study of Osteoporotic Fractures (2006)Poor Sleep Is Associated With…Insomnia Comorbidity and Impact and Hypnotic Use by Age Group in a National Survey Population Aged 16 to 74 Years (2006)Insomnia Comorbidity and Impa…Prevalence and Comorbidity of Insomnia and Effect on Functioning in Elderly Populations (2005)Prevalence and Comorbidity of…Normative Sleep Data, Cognitive Function and Daily Living Activities in Older Adults in the Community (2005)Normative Sleep Data, Cogniti…Sleep disturbances and chronic disease in older adults (2004)Sleep disturbances and chroni…Sustained Efficacy of Eszopiclone Over 6 Months of Nightly Treatment: Results of a Randomized, Double-Blind, Placebo-Controlled Study in Adults with Chronic Insomnia (2003)Sustained Efficacy of Eszopic…Healthy Older Adults’ Sleep Predicts All-Cause Mortality at 4 to 19 Years of Follow-Up (2003)Healthy Older Adults’ Sleep P…Validation of the Insomnia Severity Index as an outcome measure for insomnia research (2001)Validation of the Insomnia Se…The Impact of Insomnia on Cognitive Functioning in Older Adults (2001)The Impact of Insomnia on Cog…Incidence and remission of insomnia among elderly adults : An epidemiologic study of 6,800 persons over three years. (1999)Incidence and remission of in…Characteristics of insomnia in the United States: results of the 1991 National Sleep Foundation Survey. I. (1999)Characteristics of insomnia i…Sleep Complaints Among Elderly Persons: An Epidemiologic Study of Three Communities (1995)Sleep Complaints Among Elderl…The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. (1992)The MOS 36-item short-form he…Insomnia and Its Treatment (1985)Insomnia and Its TreatmentAlliance for Sleep Clinical Practice Guideline on Switching or Deprescribing Hypnotic Medications for Insomnia (2023)Alliance for Sleep Clinical P…Efficacy and safety of Z-substances in the management of insomnia in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing (2022)Efficacy and safety of Z-subs…Long-term effectiveness and safety of lemborexant in adults with insomnia disorder: results from a phase 3 randomized clinical trial (2021)Long-term effectiveness and s…Eszopiclone for insomnia (2018)Eszopiclone for insomniaThe impact of eszopiclone on sleep and cognition in patients with schizophrenia and insomnia: A double-blind, randomized, placebo-controlled trial (2014)The impact of eszopiclone on …Insomnia Moderates Outcome of Serotonin-Selective Reuptake Inhibitor Treatment in Depressed Youth (2012)Insomnia Moderates Outcome of…Drugs for insomnia (2012)Drugs for insomniaDevelopment of a Rating Scale for Primary Depressive Illness (1967)A Diagnostic Interview (1978)The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research (1989)Comparative meta-analysis of behavioral interventions for insomnia and their efficacy in middle-aged adults and in older adults 55+ years of age. (2006)Sleep Loss Activates Cellular Inflammatory Signaling (2008)A Randomized, Placebo-Controlled Trial of Online Cognitive Behavioral Therapy for Chronic Insomnia Disorder Delivered via an Automated Media-Rich Web Application (2012)The International Classification of Sleep Disorders (1991)The Insomnia Severity Index: Psychometric Indicators to Detect Insomnia Cases and Evaluate Treatment Response (2011)Diagnostic and Statistical Manual of Mental Disorders (2013)The effects of physical activity on sleep: a meta-analytic review (2015)European guideline for the diagnosis and treatment of insomnia (2017)Behavioral and Pharmacological Therapies for Late-Life Insomnia (1999)Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications (2001)Recommendations on Evidence Needed to Support Measurement Equivalence between Electronic and Paper-Based Patient-Reported Outcome (PRO) Measures: ISPOR ePRO Good Research Practices Task Force Report (2008)Efficacy of Brief Behavioral Treatment for Chronic Insomnia in Older Adults (2011)Safety and efficacy of suvorexant during 1-year treatment of insomnia with subsequent abrupt treatment discontinuation: a phase 3 randomised, double-blind, placebo-controlled trial (2014)VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE (1958)Automatic Sleep/Wake Identification From Wrist Activity (1992)The Role of Actigraphy in the Study of Sleep and Circadian Rhythms (2003)Self-Reported Sleep Quality Predicts Poor Cognitive Performance in Healthy Older Adults (2009)Sleep and its disorders in aging populations (2009)Self-reported sleep duration and cognitive performance in older adults: a systematic review and meta-analysis (2015)Mortality Associated With Sleep Duration and Insomnia (2002)A Systematic Review Assessing Bidirectionality between Sleep Disturbances, Anxiety, and Depression (2013)The Association of Sleep and Pain: An Update and a Path Forward (2013)Comorbidity of Chronic Insomnia With Medical Problems (2007)Connections between sleep and cognition in older adults (2014)Sleep in Normal Aging (2017)Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy (1994)Epidemiology of Insomnia, Depression, and Anxiety (2005)The MOS 36-Item Short-Form Health Survey (SF-36) (1993)Short screening scales to monitor population prevalences and trends in non-specific psychological distress (2002)A Brief Measure for Assessing Generalized Anxiety Disorder (2006)Sleep disturbance in cancer patients (2002)Sleep disturbances, work stress and work hours (2002)Use of sleep hygiene in the treatment of insomnia (2003)Age-related sleep change (2004)
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References

  • 1992The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.33,714 cited
  • 2001Validation of the Insomnia Severity Index as an outcome measure for insomnia research8,058 cited
  • 1995Sleep Complaints Among Elderly Persons: An Epidemiologic Study of Three Communities1,610 cited
  • 2004Sleep disturbances and chronic disease in older adults1,203 cited
  • 1985Insomnia and Its Treatment1,071 cited
  • 1999Characteristics of insomnia in the United States: results of the 1991 National Sleep Foundation Survey. I.776 cited
  • 2003Sustained Efficacy of Eszopiclone Over 6 Months of Nightly Treatment: Results of a Randomized, Double-Blind, Placebo-Controlled Study in Adults with Chronic Insomnia630 cited
  • 2003Healthy Older Adults’ Sleep Predicts All-Cause Mortality at 4 to 19 Years of Follow-Up586 cited
  • 2006Poor Sleep Is Associated With Impaired Cognitive Function in Older Women: The Study of Osteoporotic Fractures440 cited
  • 1999Incidence and remission of insomnia among elderly adults : An epidemiologic study of 6,800 persons over three years.399 cited
  • 2001The Impact of Insomnia on Cognitive Functioning in Older Adults368 cited
  • 2005Normative Sleep Data, Cognitive Function and Daily Living Activities in Older Adults in the Community301 cited
  • 2006Sleep: A Marker of Physical and Mental Health in the Elderly286 cited

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2005
Prevalence and Comorbidity of Insomnia and Effect on Functioning in Elderly Populations
282 cited
  • 2007Poor Sleep is Associated with Poorer Physical Performance and Greater Functional Limitations in Older Women277 cited
  • 2006Insomnia Comorbidity and Impact and Hypnotic Use by Age Group in a National Survey Population Aged 16 to 74 Years274 cited
  • Cited by

    • 2021Long-term effectiveness and safety of lemborexant in adults with insomnia disorder: results from a phase 3 randomized clinical trial91 cited
    • 2012Insomnia Moderates Outcome of Serotonin-Selective Reuptake Inhibitor Treatment in Depressed Youth73 cited
    • 2012Drugs for insomnia70 cited
    • 2022Efficacy and safety of Z-substances in the management of insomnia in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing63 cited
    • 2023Alliance for Sleep Clinical Practice Guideline on Switching or Deprescribing Hypnotic Medications for Insomnia59 cited
    • 2014The impact of eszopiclone on sleep and cognition in patients with schizophrenia and insomnia: A double-blind, randomized, placebo-controlled trial59 cited
    • 2018Eszopiclone for insomnia57 cited