Modes of research in genetics

Abstract

methods of research.I shall try to point out, with reference to an old problem, where it would seem that current methods have encountered definite limitations and wherein lies the special value of each.If I can succeed in doing even so much, something will have been gained, even though it is not now possible to show any results achieved by new points of view and new methods in the field to be discussed.The problem to which attention is invited is one of the most fundamental of biology, the problem of heredity.In what is to follow I shall try to do three things.First: to define the problem in strictly objec- tive terms, free if possible from any implications which have grown out of theories of the hereditary process.Second: to examine critically the four chief methods of investigation by which attempts have been made to solve the problem, endeavoring to show in how far each has failed to take us beyond a certain point in our understanding of the matter.Third: to draw such conclusions from this methodological critique in regard to the most promising lines for future attack as seem war- ranted by the results. I. THE PROBLEM OF HEREDITYThe problem of heredity can be easily defined in a general way in terms which are perfectly

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