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Introduction / Eva M. Neumann-Held and Christoph Rehmann-Sutter 1 I. Empirical Approaches 1. Genome Analysis and Developmental Biology: The Nematode Caenorhabditis elegans as a Model System / Thomas R. Burglin 15 2. Genes and Form: Inherency in the Evolution of Developmental Mechanisms / Stuart A. Newman and Gerd B. Muller 38 II. Looking Back into History 3. From Genes as Determinants to DNA as Resource: Historical Notes on Development and Genetics / Sahotra Sarkar 77 III. Theorizing Genes 4. The Origin of Species: A Structuralist Approach / Gerry Webster and Brian C. Goodwin 99 5. On the Problem of the Molecular versus the Organismic Approach in Biology / Ulrich Wolf 135 6. Genes, Development, and Semiosis / Jesper Hoffmeyer 152 7. The Fearless Vampire Conservator: Philip Kitcher, Genetic Determinism, and the Informational Gene / Paul E. Griffiths 175 8. Genetics from an Evolutionary Process Perspective / James Griesemer 199 9. Genes-Causes-Codes: Deciphering DNA's Ontological Privilege / Eva M. Newmann-Held 238 10. Boundaries and (Constructive) Interaction / Susan Oyama 272 11. Beyond the Gene but Beneath the Skin / Evelyn Fox Keller 290 12. Poiesis and Praxis: Two Modes of Understanding Development / Christoph Rehmann-Sutter 313 IV. Social and Ethical Implications 13. Developmental Emergence, Genes, and Responsible Science / Brian C. Goodwin 337 14. Nothing Like a Gene / Jackie Leach Scully 349 Contributors 365 Index 369
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