Obtaining Individual Patient Data from Randomised Controlled Trials

Mike J Clarke · Lesley A. Stewart

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Meta-analysis and systematic reviews Statistical Methods in Clinical Trials Delphi Technique in Research

Abstract

This chapter contains section titled: Summary Points What are Individual Patient Data Reviews? Improved Follow—Up Time—to—Event Analyses Estimating Time—to—Event Outcomes from Published Information Effects in Patient Subgroups and on Different Outcomes How to Obtain Data that are as Complete as Possible What if IPD are not Available? Potential Disadvantages of IPD Reviews Examples of how the Collection of IPD can make a Difference to the Findings of a Review Conclusion

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References

1998Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints 1993Meta-analysis of the literature or of individual patient data: is there a difference?1993The Cochrane Collaboration: Preparing, Maintaining, and Disseminating Systematic Reviews of the Effects of Health Care 1995Practical methodology of meta‐analyses (overviews) using updated individual patient data 1993Publication Bias: The Problem That Won't Go Away 1995A comparison of meta-analytic results using literature vs individual patient data. Paternal cell immunization for recurrent miscarriage 1998Individual patient data meta-analysis in cancer

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