Importance of Transparent Reporting of Health Research

Douglas G. Altman · David Moher

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Meta-analysis and systematic reviews Academic Publishing and Open Access Pharmaceutical industry and healthcare

Abstract

Research related to the health of humans should have the potential to advance scientific understanding or improve the treatment or prevention of disease. Reports of clinical research are important to many groups, especially other researchers, clinicians, systematic reviewers, and patients. Nonpublication of the findings of some research studies, either through suppression of complete studies or selective reporting within publications, always diminishes the evidence base. Inadequate reporting of methodology can also seriously impede assessment of the reliability of published articles. Reporting guidelines provide structured advice on the minimum information to be included in an article reporting a particular type of health research. Journals have a key role in helping to improve the literature by requiring the full and transparent reporting of research. Web-enabled reporting guidelines are one possibility as are machine'readable language software to help populate checklists automatically.

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2010CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials 2009Avoidable waste in the production and reporting of research evidence 2004Empirical Evidence for Selective Reporting of Outcomes in Randomized Trials 2008Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias 2004The Cochrane Database of Systematic Reviews 2012Scientific Utopia 2011Negative results are disappearing from most disciplines and countries 2012Influence of Reported Study Design Characteristics on Intervention Effect Estimates From Randomized, Controlled Trials

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