Article2010

Sleep Duration and Mortality According to Health Status in Older Adults

Arthur Eumann Mesas · Esther López‐García · Luz María León-Muñoz · Pilar Guallar‐Castillón · Fernando Rodríguez‐Artalejo

162 citations0/0 files storedJournal of the American Geriatrics Society

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Abstract

OBJECTIVES: To examine the association between usual sleep duration and mortality according to physical and mental health status in older adults. DESIGN: Prospective study conducted from 2001 to 2008. SETTING: Community-based study. PARTICIPANTS: Cohort study of 3,820 persons representative of the noninstitutionalized population aged 60 and older in Spain. MEASUREMENTS: Sleep duration was self-reported at baseline. Analyses were performed using Cox regression and adjusted for the main confounders. The analyses were then stratified according to numerous indicators of health status. RESULTS: During follow-up, 897 persons died. Mortality was higher in those who slept 8 hours (relative risk (RR)=1.34, 95% confidence interval (CI)=1.02-1.76), 9 hours (RR 1.48, 95% CI=1.12-1.96), 10 hours (RR 1.73, 95% CI=1.30-2.29) and 11 hours or more (RR 1.66, 95% CI=1.23-2.24) than in those who slept 7 hours (P for trend <.001). The association between long sleep duration (≥10 vs 7 hours) and mortality was observed even in persons with good health status: optimal perceived health, good cognitive function (Mini-Mental State Examination score >27), no depression, quality of life better than the cohort median (Medical Outcomes Study 36-item Short Form Survey Physical Component Summary score ≥46 and Mental Component Summary score ≥52), and without disability in instrumental activities of daily living. Sleeping 6 hours or less was not associated with higher mortality than sleeping 7 hours in persons with good health status. CONCLUSION: Self-reported sleep duration was associated with 7-year mortality in this cohort of older adults, even when adjusted for health status. Further research is needed to determine the mechanisms and clinical implications of these findings.

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References

1999Impact of sleep debt on metabolic and endocrine function 2002Mortality Associated With Sleep Duration and Insomnia 2003A Prospective Study of Sleep Duration and Coronary Heart Disease in Women 2004A Prospective Study of Sleep Duration and Mortality Risk in Women 1999Comparison between subjective and actigraphic measurement of sleep and sleep rhythms 1989AGREEMENT BETWEEN QUESTIONNAIRE DATA AND MEDICAL RECORDS 2003Healthy Older Adults’ Sleep Predicts All-Cause Mortality at 4 to 19 Years of Follow-Up 2006Correlates of Long Sleep Duration

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