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The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy')

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References

19873,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.458 cited
1988MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons312 cited
1987In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain297 cited
19943,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans289 cited
1988Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration245 cited

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2005Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy238 cited
2000The relative contributions of ecstasy and cannabis to cognitive impairment225 cited
2002The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats221 cited
2003Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms199 cited
2003Altered states: the clinical effects of Ecstasy190 cited
2006Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?189 cited
20013,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose

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185 cited

2004A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response181 cited

2003Acute, sub‐acute and long‐term subjective consequences of ‘ecstasy’ (MDMA) consumption in 430 regular users171 cited

2004Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function153 cited

2000The serotonin uptake inhibitor citalopram reduces acute cardiovascular and vegetative effects of 3, 4-methylenedioxymethamphetamine (‘Ecstasy’) in healthy volunteers144 cited

2006Elevated impulsivity and impaired decision-making cognition in heavy users of MDMA (“Ecstasy”)140 cited

2004Residual neuropsychological effects of illicit 3,4-methylenedioxymethamphetamine (MDMA) in individuals with minimal exposure to other drugs138 cited

2006Ecstasy: Are animal data consistent between species and can they translate to humans?126 cited

2003Increased Anxiety 3 Months after Brief Exposure to MDMA (‘Ecstasy’) in Rats: Association with Altered 5-HT Transporter and Receptor Density122 cited

2002Sub-acute effects of MDMA (±3,4-methylenedioxymethamphetamine, "ecstasy") on mood: evidence of gender differences119 cited