Articlebronze2001

Genetics of Cognition: Outline of a Collaborative Twin Study

Margaret J. Wright · Eco J. C. de Geus · Juko Ando · Michelle Luciano A · Danielle Posthuma B · Yutaka Ono +11 more

170 citations0/0 files storedTwin Research

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Cognitive Abilities and Testing Genetic Associations and Epidemiology Intergenerational and Educational Inequality Studies

Abstract

A multidisciplinary collaborative study examining cognition in a large sample of twins is outlined. A common experimental protocol and design is used in The Netherlands, Australia and Japan to measure cognitive ability using traditional IQ measures (i.e., psychometric IQ), processing speed (e.g., reaction time [RT] and inspection time [IT]), and working memory (e.g., spatial span, delayed response [DR] performance). The main aim is to investigate the genetic covariation among these cognitive phenotypes in order to use the correlated biological markers in future linkage and association analyses to detect quantitative-trait loci (QTLs). We outline the study and methodology, and report results from our preliminary analyses that examines the heritability of processing speed and working memory indices, and their phenotypic correlation with IQ. Heritability of Full Scale IQ was 87% in the Netherlands, 83% in Australia, and 71% in Japan. Heritability estimates for processing speed and working memory indices ranged from 33-64%. Associations of IQ with RT and IT (-0.28 to -0.36) replicated previous findings with those of higher cognitive ability showing faster speed of processing. Similarly, significant correlations were indicated between IQ and the spatial span working memory task (storage [0.31], executive processing [0.37]) and the DR working memory task (0.25), with those of higher cognitive ability showing better memory performance. These analyses establish the heritability of the processing speed and working memory measures to be used in our collaborative twin study of cognition, and support the findings that individual differences in processing speed and working memory may underlie individual differences in psychometric IQ.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 170 citations exist upstream.

References

1974Working Memory 1996The processing-speed theory of adult age differences in cognition.1992Working Memory 1998The g factor: the science of mental ability 1990Reasoning ability is (little more than) working-memory capacity?!1990What one intelligence test measures: A theoretical account of the processing in the Raven Progressive Matrices Test.1996Working memory and language comprehension: A meta-analysis 1974Manual for the Wechsler intelligence scale for children

Cited by

2001Genetic Covariance Among Measures of Information Processing Speed, Working Memory, and IQ 2003Genetic Correlations Between Brain Volumes and the WAIS-III Dimensions of Verbal Comprehension, Working Memory, Perceptual Organization, and Processing Speed 2001Perceptual Speed and IQ Are Associated Through Common Genetic Factors 2010Trait and State Differences in Working Memory Capacity 2014Genome‐wide screening for DNA variants associated with reading and language traits

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.