Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users

Una D. McCann · George A. Ricaurte · Domenic A. Ciraulo

134 citations0/0 files storedJournal of Clinical Psychopharmacology

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Psychedelics and Drug Studies Neurotransmitter Receptor Influence on Behavior Forensic Toxicology and Drug Analysis

Abstract

Two persons are described who demonstrated prolonged neuropsychiatric syndromes after the ingestion of large doses of (+-)-3,4-methylenedioxymethamphetamine (MDMA), a recreationally used amphetamine analog. These cases suggest that MDMA, known to be neurotoxic to serotonin neurons in several experimental animals, may also produce untoward effects in humans. In addition, they provide evidence that ingestion of large doses of MDMA can produce lasting adverse functional consequences in vulnerable persons.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 134 citations exist upstream.

References

1987Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.19873,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.1987Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.1988MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons 1988(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates 1988Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

Cited by

2006Ecstasy: Are animal data consistent between species and can they translate to humans?1996Adverse Reactions with 3,4-Methylenedioxymethamphetamine (MDMA; ???Ecstasy???)2001Former chronic methylenedioxymethamphetamine (MDMA or ecstasy) users report mild depressive symptoms 2013MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational ‘Ecstasy’ users 2000High Intensity Dependence of Auditory Evoked Dipole Source Activity Indicates Decreased Serotonergic Activity in Abstinent Ecstasy (MDMA) Users

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.