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A decade of innovation in pharmaceutical R&D: the Chorus model
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A decade of innovation in pharmaceutical R&D: the Chorus model (2014)A decade of innovation in pharmaceutical …Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework (2014)Lessons learned from the fate…The R&D Cost of a New Medicine (2012)The R&D Cost of a New MedicineDiagnosing the decline in pharmaceutical R&D efficiency (2012)Diagnosing the decline in pha…The productivity crisis in pharmaceutical R&D (2011)The productivity crisis in ph…How to improve R&D productivity: the pharmaceutical industry's grand challenge (2010)How to improve R&D productivi…Spending on new drug development1 (2009)Spending on new drug developm…Lessons from 60 years of pharmaceutical innovation (2009)Lessons from 60 years of phar…Rebuilding the R&D engine in big pharma. (2008)Rebuilding the R&D engine in …Achieving end-to-end success in the clinic: Pfizer’s learnings on R&D productivity (2021)Achieving end-to-end success …Measuring the effectiveness and impact of an open innovation platform (2017)Measuring the effectiveness a…Can the pharmaceutical industry reduce attrition rates? (2004)Changing R&D models in research-based pharmaceutical companies (2016)When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility Crisis (2016)A Decade of FDA-Approved Drugs (2010–2019): Trends and Future Directions (2021)Interorganizational Collaboration and the Locus of Innovation: Networks of Learning in Biotechnology (1996)The price of innovation: new estimates of drug development costs (2003)The black swan: the impact of the highly improbable (2007)THE WORLD MEDICINES SITUATION 2011 (2011)Drug discovery in pharmaceutical industry: productivity challenges and trends (2012)Rise and fall of modern medicine (1999)Are Ideas Getting Harder to Find? (2020)Generating Theory by Abduction (2021)Protecting Their Intellectual Assets: Appropriability Conditions and Why U.S. Manufacturing Firms Patent (or Not) (2000)How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment (2021)A Proof for the Queuing Formula: L = λ W (1961)The Goal: A Process of Ongoing Improvement (1984)Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018 (2020)Open Innovation: The New Imperative for Creating and Profiting from Technology (2003)Innovation in the pharmaceutical industry: New estimates of R&D costs (2016)Leveraging Research Failures to Accelerate Drug Discovery and Development (2019)Open Innovation in the Agri-Food Sector: Perspectives from a Systematic Literature Review and a Structured Survey in MSMEs (2021)Open Innovation in Healthcare Ecosystem: A Systematic Review (2024)Scale, Scope, and Spillovers: The Determinants of Research Productivity in Drug Discovery (1996)Estimating The Cost Of New Drug Development: Is It Really $802 Million? (2006)How Drugs are Developed and Approved by the FDA: Current Process and Future Directions (2014)Market size and pharmaceutical innovation (2015)Costs of Drug Development and Research and Development Intensity in the US, 2000-2018 (2024)The impact of mergers on pharmaceutical R&D (2011)Big Pharma, little science? (2012)Financialized Corporations in a National Innovation System: The U.S. Pharmaceutical Industry (2018)Incremental cost per quality-adjusted life year gained? The need for alternative methods to evaluate medical interventions for ultra-rare disorders (2014)Orphan drugs policies: a suitable case for treatment (2014)Improving clinical trials for cardiovascular diseases: a position paper from the Cardiovascular Round Table of the European Society of Cardiology (2015)
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References

  • 2010How to improve R&D productivity: the pharmaceutical industry's grand challenge3,562 cited
  • 2012Diagnosing the decline in pharmaceutical R&D efficiency1,978 cited
  • 2014Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework1,344 cited
  • 2009Lessons from 60 years of pharmaceutical innovation1,207 cited
  • 2011The productivity crisis in pharmaceutical R&D918 cited
  • 2009Spending on new drug development1277 cited
  • 2008Rebuilding the R&D engine in big pharma.230 cited
  • 2012The R&D Cost of a New Medicine90 cited

Cited by

  • 2021Achieving end-to-end success in the clinic: Pfizer’s learnings on R&D productivity66 cited
  • 2017Measuring the effectiveness and impact of an open innovation platform41 cited

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