Article2008

Obsessive–Compulsive Disorder: Influence of Age at Onset on Comorbidity Patterns

Maria Alice de Mathis · Maria Conceição do Rosário · Juliana Belo Diniz · Albina Rodrigues Torres · Roseli Gedanke Shavitt · Ygor Arzeno Ferrão +3 more

101 citations0/0 files storedEuropean Psychiatry

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Obsessive-Compulsive Spectrum Disorders Psychoanalysis and Psychopathology Research Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Abstract

PURPOSE: This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset. METHODS: Three hundred and thirty OCD patients were consecutively recruited and interviewed using the following structured interviews: Yale-Brown Obsessive Compulsive Scale; Yale Global Tic Severity Scale and the Structured Clinical Interview for DSM-IV. Data were analyzed with regression and cluster analysis. RESULTS: Lower age at onset was associated with a higher probability of having comorbidity with tic, anxiety, somatoform, eating and impulse-control disorders. Longer illness duration was associated with lower chance of having tics. Female gender was associated with anxiety, eating and impulse-control disorders. Tic disorders were associated with anxiety disorders and attention-deficit/hyperactivity disorder. No cut-off age at onset was found to clearly divide the sample in homogeneous subgroups. However, cluster analyses revealed that differences started to emerge at the age of 10 and were more pronounced at the age of 17, suggesting that these were the best cut-off points on this sample. CONCLUSIONS: Age at onset is associated with specific comorbidity patterns in OCD patients. More prominent differences are obtained when analyzing age at onset as an absolute value.

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References

1989The Yale-Brown Obsessive Compulsive Scale 1989The Yale Global Tic Severity Scale: Initial Testing of a Clinician-Rated Scale of Tic Severity 2005A Multidimensional Model of Obsessive-Compulsive Disorder 1995A family study of obsessive-compulsive disorder 1987Fears, phobias, and rituals 1989Obsessive-Compulsive Disorder in Children and Adolescents 1997Symptoms of obsessive-compulsive disorder 2000A Family Study of Obsessive-compulsive Disorder

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