Simultaneous monoamine histofluorescence and neuropeptide immunocytochemistry: II. Correlative distribution of catecholamine varicosities and magnocellular neurosecretory neurons in the rat supraoptic and paraventricular nuclei

Thomas H. Mc Neill · John R. Sladek

166 citations0/0 files storedThe Journal of Comparative Neurology

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Neuroendocrine regulation and behavior Neuroscience and Neuropharmacology Research Neuropeptides and Animal Physiology

Abstract

The comparative morphology of catecholamine (CA) varicosities and neurophysin (NP)-containing perikarya of the supraoptic (SON) and paraventricular nuclei (PVN) was examined. The major CA innervation to the SON and PVN did not coexist with the major distribution of magnocellular perikarya, but was located peripheral to the nuclei. A dense distribution of CA varicosities was found ventral to the neurosecretory perikarya of the SON and overlapped numerous immunoreactive oxytocin- and vasopressin-containing neuritic profiles. Examination of Golgi-stained sections revealed that dendrites from SON perikarya projected to the CA zone and were likely candidates for the processes identified immunocytochemically. In addition, a heterogenous distribution of axosomatic contacts was found within the SON which suggested a preferential innervation of VP-containing neurons. The densest concentration of CA varicosities in the PVN occurred in the periventricular region adjacent to the third ventricle and in the contiguous parvocellular portion of the PVN. These CA varicosities overlapped scattered oxytocinerigic perikarya in both areas. In addition the ventromedial as well as the dorsolateral subnuclei of the PVN were contacted by CA varicosities; this heterogeneous distribution suggests that the each subnucleus of the PVN with its individual hypothalamic, neurohypophyseal, brainstem, or cortical projections may possibly receive a catecholaminergic innervation by a select group of CA cells or nuclear groups from the brain stem.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 166 citations exist upstream.

References

1980Subnuclei in the rat hypothalamic paraventricular nucleus: A cytoarchitectural, horseradish peroxidase and immunocytochemical analysis 1975Immunofluorescence of vasopressin and oxytocin in the rat hypothalamo-neurohypophyseal system 1975DISTRIBUTION OF OXYTOCIN AND VASOPRESSIN IN THE RAT SUPRAOPTIC AND PARAVENTRICULAR NUCLEUS 1966Magnocellular neurosecretory centers in the rat hypothalamus

Cited by

1982Magnocellular neuropeptidergic neurons in hypothalamus: Increases in membrane apposition and number of specialized synapses from pregnancy to lactation 1997Autoinhibition of Supraoptic Nucleus Vasopressin Neurons In Vivo: A Combined Retrodialysis/Electrophysiological Study in Rats 1998Noradrenergic Excitation of Magnocellular Neurons in the Rat Hypothalamic Paraventricular Nucleus via Intranuclear Glutamatergic Circuits 1983The Organization and Biochemical Specificity of Afferent Projections to the Paraventricular and Supraoptic Nuclei 1995Involvement of the noradrenergic afferents from the nucleus tractus solitarii to the supraoptic nucleus in oxytocin release after peripheral cholecystokinin octapeptide in the rat 1989Dorsomedial medulla stimulation activates rat supraoptic oxytocin and vasopressin neurones through different pathways.1982Immunocytochemical, Golgi and electron microscopic characterization of putative dendrites in the ventral glial lamina of the rat supraoptic nucleus

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.