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Glutathione and N-Acetylcysteine Conjugates of α-Methyldopamine Produce Serotonergic Neurotoxicity: Possible Role in Methylenedioxyamphetamine-Mediated Neurotoxicity

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References

19873,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.458 cited
1987Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.453 cited
1985Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals367 cited
1988Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration245 cited
1987Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat183 cited
1990Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors131 cited

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2011Lost in translation: preclinical studies on 3,4‐methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans74 cited

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