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Despite the growing importance of universityindustry relationships (UIR) and the high proportion of such linkages failing, little is known on barriers to the formation and development of these relationships. This exploratory study aims at exploring such barriers. Organisational culture difference (OCD), such as differences in motivation, time orientation and market orientation (MO), were found to negatively effect UIR formation and development. Negative perceptions of universities' MO clearly emerged from the data. Indeed, universities' MO should be considered as a broad concept based on all value creation factors, not just 'business skills'. Finally, internal structures, bureaucracy and academics' individualistic way of working were identified as further factors potentially hindering universityindustry relationships. Managerial implications involve recognising the role of individuals, their passion and experience, in overcoming the barriers identified in this study.
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