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Industry-science relationship is considered to be a very important part of the innovation system and it represents one of the crucial factors in national innovation capacity. Extant studies show that a significant proportion of the products and processes that are currently sold and used could not have been developed without academic research. Both industry and academia can benefit from this relationship. Research focus in this paper is on interactions between science and the industry from the researchers’ point of view based on field study in Croatia. This paper seeks to develop understanding of determinants of collaboration intensity with industry and scientists satisfaction in this relationship. It explores scientists’ motivations to collaborate and perceptions of barriers for collaboration as well as how they perceive the other side in this relationship. Research findings show strong scientist interest in the collaboration with industry. Significant motives that can explain their interest are intellectual challenge and additional income. Scientists find more powerful obstacles in their internal organizations than in external relationship with industry. They are persuaded that industry is not as interested in collaboration as they are. Less critical are those group of scientists who have already built closer working ties with industry.
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