Article2004

Burden of Medical Illness in Women With Depression and Posttraumatic Stress Disorder

Susan M. Frayne · Margaret R. Seaver · Susan A. Loveland · C L Christiansen · Avron Spiro · Victoria Anne Parker +1 more

125 citations0/0 files storedArchives of Internal Medicine

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Posttraumatic Stress Disorder Research Psychosomatic Disorders and Their Treatments Migration, Health and Trauma

Abstract

BACKGROUND: Depression and posttraumatic stress disorder (PTSD) are important women's health issues. Depression is known to be associated with poor physical health; however, associations between physical health and PTSD, a common comorbidity of depression, have received less attention. OBJECTIVES: To examine number of medical symptoms and physical health status in women with PTSD across age strata and benchmark them against those of women with depression alone or with neither depression nor PTSD. METHODS: A random sample of Veterans Health Administration enrollees received a mailed survey in 1999-2000 (response rate, 63%). The 30 865 women respondents were categorized according to whether a health care provider had ever told them that they had PTSD, depression (without PTSD), or neither. Outcomes were self-reported medical conditions and physical health status measured with the Veterans SF-36 instrument, a version of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) modified for use in veteran populations. RESULTS: Across age strata, women with PTSD (n = 4348) had more medical conditions and worse physical health status (physical functioning, role limitations due to physical problems, bodily pain, and energy/vitality scales from the Veterans SF-36) than women with depression alone (n = 7580) or neither (n = 18 937). In age-adjusted analyses, the Physical Component Summary score was on average 3.4 points lower in women with depression alone and 6.3 points lower in women with PTSD than in women with neither (P<.001). CONCLUSIONS: Posttraumatic stress disorder is associated with a greater burden of medical illness than is seen with depression alone. The presence of PTSD may account for an important component of the excess medical morbidity and functional status limitations seen in women with depression.

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1992The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.2003SF-36 health survey: Manual and interpretation guide 1995Posttraumatic Stress Disorder in the National Comorbidity Survey 1997Self-Rated Health and Mortality: A Review of Twenty-Seven Community Studies 1997Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study 1982Mail and Telephone Surveys: The Total Design Method.1993The MOS 36-Item Short-Form Health Survey (SF-36)1979Mail and Telephone Surveys: The Total Design Method.

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2019Physical health burden of PTSD, depression, and their comorbidity in the U.S. veteran population: Morbidity, functioning, and disability 2020Economic evaluations and cost analyses in posttraumatic stress disorder: a systematic review 2006Post-traumatic Stress Disorder and Diabetes: Co-Morbidity and Outcomes in a Male Veterans Sample 2015Assessment of the Healthcare Needs and Barriers to VA Use Experienced by Women Veterans 2015A Randomized Clinical Trial of Primary Care Brief Mindfulness Training for Veterans With PTSD

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