Article2001

Neural Correlates of Traumatic Memories in Posttraumatic Stress Disorder: A Functional MRI Investigation

Ruth A. Lanius · Peter Williamson · Maria Densmore · Kristine Boksman · Madhulika A. Gupta · Richard W. J. Neufeld +2 more

520 citations0/0 files storedAmerican Journal of Psychiatry

No readable copy stored yet — this record is metadata only.

Posttraumatic Stress Disorder Research Psychoanalysis and Psychopathology Research Memory Processes and Influences

Abstract

OBJECTIVE: The neuronal circuitry underlying posttraumatic stress disorder (PTSD) was studied in traumatized subjects with and without PTSD. METHOD: Traumatized subjects with (N=9) and without (N=9) PTSD were studied by using the script-driven symptom provocation paradigm adapted to functional magnetic resonance imaging at a 4-T field strength. RESULTS: PTSD subjects showed significantly less activation of the thalamus, the anterior cingulate gyrus (Brodmann's area 32), and the medial frontal gyrus (Brodmann's area 10/11) than did the comparison subjects. CONCLUSIONS: The findings suggest anterior cingulate, frontal, and thalamic involvement in the neuronal circuitry underlying PTSD.

Citations in this library

Stored only when both papers are in the corpus — 520 citations exist upstream.

References

1995The development of a Clinician-Administered PTSD Scale 1996A Symptom Provocation Study of Posttraumatic Stress Disorder Using Positron Emission Tomography and Script-Driven Imagery 1999Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study 1999Neural Correlates of Memories of Childhood Sexual Abuse in Women With and Without Posttraumatic Stress Disorder 1999Regional Cerebral Blood Flow During Script-Driven Imagery in Childhood Sexual Abuse-Related PTSD: A PET Investigation 1999Brain activation in PTSD in response to trauma-related stimuli

Cited by

2006Clinical Implications of Neuroscience Research in PTSD 2002Brain activation during script-driven imagery induced dissociative responses in PTSD: a functional magnetic resonance imaging investigation 2003Neuroimaging Studies of Amygdala Function in Anxiety Disorders 2010Dissociation Following Traumatic Stress 2018Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man 2012Quantitative meta-analysis of neural activity in posttraumatic stress disorder 2006

Imported from OpenAlex (CC0) — nothing here is generated.