Seroprevalence of transfusion transmissible infections among healthy blood donors at KIMS blood bank

Abstract

Background: Safe blood is a critical component in improving health care and in preventing the spread of infectious diseases. Aims & Objectives: Blood transfusion can cause the transmission of infectious to recipients. This is an important mode of infection. The aim of the study was to assess the prevalence of such type of infection among blood donors and to compare the seroprevalence of transfusion transmitted diseases in blood donors. Retrospective study was conducted for 5 years from January-2009 to December-2013 at KIMS Blood Bank, Secunderabad. Materials and methods: All donors reporting to the blood bank during the period January-2009 to December-2013 were screened for human immunodeficiency virus (HIV) 1 & 2, hepatitis C viruses, malaria and syphilis. Screening of HIV, hepatitis B and hepatitis C viruses were done by chemillumiencies and syphilis was screened by RPR method. Results: A total of 39780 voluntary blood donors were screened, of which 38697 were males and 1083 were females. Seropositivity of HIV, hepatitis B, hepatitis C viruses & syphilis were 0.26%, 1.28%, 0.51% and 0.03% respectively. No blood donors test showed positivity for malaria parasite. Conclusion: With the implementation of strict donor selection criteria and use of sensitive screening test, it may be possible to reduce the incidence of TTIs. Keywords: human immunodeficiency virus; hepatitis B virus; hepatitis C virus; seroprevalence; transfusion transmitted infections

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